Location: Ashburn, VA
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Showing 251 results for the keyword: Lung
National Cancer Institute (NCI) Closest clinic: 21 miles Period: January 21, 2011 - January 31, 2018
Background: - The current standard of care for advanced lung cancer and cancers of the thymus consists primarily of chemotherapy treatment. The drugs used for chemotherapy depend on the classification of the cancer in different categories that are based on the appearance of the cancer in the micro...
National Cancer Institute (NCI) Closest clinic: 21 miles Period: May 3, 2016 - June 30, 2018
Background: CRLX101 consists of a sugar molecule cyclodextrin linked to a chemotherapy drug called camptothecin. The combined molecule or nanoparticle drug conjugate travels through the blood. Once inside cancer cells, the chemotherapy drug is released from the molecule. Olaparib is a drug that may stop ...
National Cancer Institute (NCI) Closest clinic: 21 miles Period: July 24, 2000 - Not defined
Background: -This protocol will provide a means for screening potential candidates for NCI Radiation Oncology Branch (ROB) protocols. Objectives: -To permit evaluation of patients referred to the NCI Radiation Oncology Branch in order to identify individuals who will be suitable candidates...
National Cancer Institute (NCI) Closest clinic: 21 miles Period: April 4, 2016 - February 1, 2021
Background: Some non-small-cell lung cancers (NSCLC) have a mutation in a gene that makes a protein called EGFR. This particular cancer can be treated with certain drugs such as Erlotinib (Tarceva), Gefitinib (Iressa) and Osimertinib (Tagrisso). But many tumors become resistant to these drugs beca...
National Heart, Lung, and Blood Institute (NHLBI) Closest clinic: 21 miles Period: June 19, 2001 - Not defined
This study will examine 1) the role of hereditary factors in cystic fibrosis; i.e., the relationship of the disease to specific gene variations, and 2) the role of bacterial products involved in lung infections substances produced by bacteria may worsen the disease. Patients with cystic fibrosis who are...
National Cancer Institute (NCI) Closest clinic: 21 miles Period: July 7, 2016 - April 29, 2019
Background: Anetumab ravtansine is a new drug. It kills cancer cells that carry mesothelin. That is a protein on the surface of tumor cells in many types of tumors, including most lung cancers. Researchers want to find a safe dose for the study drug for lung cancer. They want to see if it can shri...
National Cancer Institute (NCI) Closest clinic: 21 miles Period: July 21, 2016 - August 3, 2028
Background: Mithramycin is a new cancer drug. In another study, people with chest cancer took the drug 6 hours a day for 7 straight days. Many of them had liver damage as a side effect. It was discovered that only people with certain genes got this side effect. Researchers want to test mithramycin...
National Cancer Institute (NCI) Closest clinic: 21 miles Period: June 18, 2015 - May 31, 2018
Background: Chemotherapy damages cancer cell DNA so the cells die and the tumor shrinks. But it may stop working in some people over time. This is partly due to efficient DNA damage repair mechanisms used by tumor cells. VX-970 may stop cancer cells from preventing the repair of DNA damaged by che...
National Cancer Institute (NCI) Closest clinic: 49 miles Period: June 2, 1995 - Not defined
The Laboratory of Human Carcinogenesis and the Pharmocogenetics Section of the Genetic Epidemiology Branch will conduct a lung cancer case-control study in Baltimore, Maryland. The primary hypothesis of the study is to determine if mutagen sensitivity, p53 induction and apoptosis in cultured lymphocytes ...
University of Pennsylvania Closest clinic: 138 miles Period: March 2017 - March 2021
Phase I study to establish safety and feasibility of intravenous or intrapleural administered lentiviral transduced huCART-meso cells with or without lymphodepletion. Intravenous administration of huCART-meso cells is planned with or without cyclophosphamide as lymphodepleting chemotherapy.
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Ashburn, United States