Location: Ashburn, VA
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Showing 651 results for the keyword: Leukemia
National Cancer Institute (NCI) Closest clinic: 21 miles Period: March 9, 2011 - Not defined
Background: Allogeneic hematopoietic stem cell transplantation (or allotransplant; donor blood stem cells) have been used with varying degrees of success as an immune therapy for blood-system cancers (leukemias, myelodysplastic syndrome, lymphomas, multiple myeloma, etc.). Some people s cancer rem...
National Heart, Lung, and Blood Institute (NHLBI) Closest clinic: 21 miles Period: August 22, 2014 - June 1, 2019
Allogeneic hematopoetic stem cell transplantation (SCT) is frequently complicated by life threatening viral reactivation. Conventional antiviral therapy is suboptimal for cytomegalovirus (CMV), adenovirus (AdV) and Epstein-Barr virus (EBV) and nonexistent for BK virus (BKV). An alternative approach to pr...
National Heart, Lung, and Blood Institute (NHLBI) Closest clinic: 21 miles Period: August 11, 2015 - April 30, 2020
Background: -Acute myeloid leukemia (AML) is a cancer of the white blood cells. It can be fatal. Standard treatment involves intensive chemotherapy. Not all treatment works. AML that has not responded to treatment (refractory) or that has returned after treatment (relapsed) is high-risk even with ...
National Cancer Institute (NCI) Closest clinic: 21 miles Period: June 19, 2002 - Not defined
Background: - Individuals may be prone to develop blood or lymph node cancers (leukemia or lymphoma) for a variety of reasons, including genetic predisposition to these cancers, environmental exposures or other medical conditions. - Studies of people and families at high risk of c...
National Heart, Lung, and Blood Institute (NHLBI) Closest clinic: 21 miles Period: April 4, 2008 - Not defined
Background: The development of new technologies now allow scientists to investigate the molecular basis and clinical manifestations of monoclonal B cell lymphocytosis (MBL), chronic lymphocytic leukemia(CLL)/small lymphocytic lymphoma (SLL), lymphoplasmacytic lymphoma (LPL)/Waldenstrom macroglobul...
Acerta Pharma BV Closest clinic: 21 miles Period: December 2014 - December 2017
This study is to determine the response to acalabrutinib in patients with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL).
OHSU Knight Cancer Institute Closest clinic: 21 miles Period: May 2012 - March 2017
This phase II trial studies how well targeted therapy works in treating patients with acute lymphoblastic leukemia or acute myelogenous leukemia that has come back after a period of improvement or does not respond to treatment. Testing patients' blood or bone marrow to find out if their type of cancer ma...
National Cancer Institute (NCI) Closest clinic: 21 miles Period: October 3, 2008 - December 31, 2018
Background: Hairy cell leukemia (HCL) is highly responsive to but not curable by cladribine (CdA). HCL responds to rituximab, which is not yet standard therapy for HCL. Patients with the CD25-negative variant (HCLv) respond poorly to initial cladribine but do respond to rituximab in anecdotal rep...
National Cancer Institute (NCI) Closest clinic: 21 miles Period: December 15, 2009 - December 31, 2018
Background: - Researchers are attempting to develop new treatments for hairy cell leukemia (HCL) that has not responded well to or has recurred after standard HCL therapies. One nonstandard treatment for HCL is rituximab, an antibody that binds to the cancer cells and helps the i...
National Cancer Institute (NCI) Closest clinic: 21 miles Period: April 2013 - June 2018
This phase II trial studies how well ibrutinib works in treating patients with hairy cell leukemia that has returned after a period of improvement. Ibrutinib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth.